Journal: Life

Article Title: Endovascular Drug Delivery

doi: 10.3390/life14040451

Figure Lengend Snippet: Bioresorbable stents.

Article Snippet: 4 , REVA Medical Fantom Bioresorbable Scaffold, (REVA, San Diego, CA, USA) , The Fantom scaffold is made of a tyrosine-derived polymer and coated with a bioresorbable polymer containing sirolimus. , [ ] .

Techniques: Polymer, Modification, Scaffolding

Journal: Life

Article Title: Endovascular Drug Delivery

doi: 10.3390/life14040451

Figure Lengend Snippet: Bioresorbable scaffold’s mode of action. ( a ) Artery with atherosclerotic plaque with significant arterial stenosis (plaque represented in red spot). ( b ) A stent is deployed at the level of the stenosis, increasing the circulating arterial lumen and, consecutively, an increase in flow. ( c ) In time, due to the intimal hyperplasia, the stent is covered with hyperplasic intima and, consecutively, new plaque is formed, obstructing the lumen again, resulting in a more significant narrowing of the artery. ( d ) A bioresorbable scaffold is placed, this time in the obstructed arterial lumen, having the same results as the stent. ( e ) In time, a bioresorbable scaffold creates a film over the atherosclerotic plaque, the endothelium. The artery expands, but the intimal hyperplasia process is at a minimum. The scaffolds are resorbed, leaving a much greater lumen and, consecutively, a greater arterial flow than the stent. In the lower image (personal collection), a stent is represented by mild signs of intimal hyperplasia at the stent level.

Article Snippet: 4 , REVA Medical Fantom Bioresorbable Scaffold, (REVA, San Diego, CA, USA) , The Fantom scaffold is made of a tyrosine-derived polymer and coated with a bioresorbable polymer containing sirolimus. , [ ] .

Techniques: